Since I didn’t see an unsubscribe link, I replied with the subject changed to “Unsubscribe”.
That didn’t mean reply some more.
When I replied to that with the subject and body changed to “Unsubscribe”, that was a less-subtle hint.
When you reply to that (maybe including a quote or some byline of mine) not along the lines of “sorry to trouble you”, I read that as “please block and report me as spam."
I know that you're a person with a job to do, but when I express a lack of interest, please take the hint. Let's not waste both of our time.